Адсорбція доксорубіцину пірогенним кремнеземом та нанокомпозитами магнетит/силоксан
A technique has been developed for immobilization of the cytostatic drug doxorubicin on the surface of magnetite nanoparticles modified with biocompatible siloxane coating and fumed silica. The processes of adsorption/desorption of doxorubicin at given surfaces were studied, high adsorption activity...
Saved in:
| Date: | 2015 |
|---|---|
| Main Authors: | , , , |
| Format: | Article |
| Language: | Ukrainian |
| Published: |
Chuiko Institute of Surface Chemistry National Academy of Sciences of Ukraine
2015
|
| Subjects: | |
| Online Access: | https://www.cpts.com.ua/index.php/cpts/article/view/352 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Journal Title: | Chemistry, Physics and Technology of Surface |
Institution
Chemistry, Physics and Technology of Surface| Summary: | A technique has been developed for immobilization of the cytostatic drug doxorubicin on the surface of magnetite nanoparticles modified with biocompatible siloxane coating and fumed silica. The processes of adsorption/desorption of doxorubicin at given surfaces were studied, high adsorption activity of siloxane surface of nanocomposites was determined with respect to doxorubicin. New nanocomposites magnetite/siloxane/doxorubicin synthesized may be promising for use in oncology, in creating the remedies for targeted delivery of drugs and as adsorption materials for intracorporal and extracorporal detoxification of the organism. |
|---|---|
| DOI: | 10.15407/hftp06.04.481 |