Влияние различных режимов криоконсервирования на сохранность стволовых кроветворных клеток костного мозга животных с аутоиммунными заболеваниями Часть 2. Оценка in vivo функционального статуса кроветворных предшественников криоконсервированного костного м

• Date: 2007
• Main Authors: Goltsev, A. N., Dubrava, T. G., Kozlova, A. Yu., Ostankov, M. V., Gurina, T. M., Kurov, A. M.
• Format: Article
• Language: English
• Published: Publishing House ‘Akademperiodyka’ of the National Academy of Sciences of Ukraine; Institute for Problems of Cryobiology and Cryomedicine 2007
• Subjects: кістковий мозок; кровотворні попередники (КУО-ГМ; КУОс); аутоімунні захворювання; ад’ювантний артрит; кріоконсервування
• Online Access: https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/512
• Journal Title: Problems of Cryobiology and Cryomedicine

Functional characteristics of bone marrow hemopoietic stem cells of healthy animals and with autoimmune diseases before and after cryopreservation with different regimens have been comparatively determined in vivo. The principle differences between an initial functional status of hemopoietic precursors of healthy donors and with autoimmune diseases, as well as its changes under similar cryopreservation conditions have been demonstrated. The “optimum” of CFUs colony-forming activity of healthy animals and those with adjuvant arthritis was noted as realised under bone marrow cryopreservation with different regimens.