Вплив іммобілізованого альбуміну на властивості композитів в системах з клітинами
The adsorption of aminosugars (N-acetyl-D-glucosamine and D-galactosamine) on the surface of initial and modified by albumin ultrafine silica was investigated. Obtained composites possess various range of bioactivity with respect to deconservated bovine gametes. Isotherms of adsorption were obtained...
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| Date: | 2013 |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | Ukrainian |
| Published: |
Chuiko Institute of Surface Chemistry National Academy of Sciences of Ukraine
2013
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| Online Access: | https://surfacezbir.com.ua/index.php/surface/article/view/527 |
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| Journal Title: | Surface |
| Download file: |  |
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Surface| Summary: | The adsorption of aminosugars (N-acetyl-D-glucosamine and D-galactosamine) on the surface of initial and modified by albumin ultrafine silica was investigated. Obtained composites possess various range of bioactivity with respect to deconservated bovine gametes. Isotherms of adsorption were obtained and parameters were calculated. It was shown that presence of СО- and СН3-groups in a N-acetyl-D-glucosamine molecule reduced its adsorption in comparison with D-galactosamine. Change of space orientation of albumin was observed as a result of adsorption of N-acetyl-D-glucosamine on the surface of ultrafine silica modified by protein. In the case of D-galactosamine similar changes were not observed. It was proved that presence of albumin in composites with aminosugars reduced bioactivity unlike composites without protein. |
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