Магнітна рідина на основі доксорубіцину для застосування в онкотерапії
Тhе water colloids nanocomposite particles of magnetite /hydroxyapatite/doxorubicin/polyethylene glycol/sodium oleate are produced. Particle represented as a structure of core-shell and contained magnetite nanoparticles on the surface modifier, the drug - an anthracycline antibiotic doxorubicin and...
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| Date: | 2014 |
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| Main Author: | |
| Format: | Article |
| Language: | Russian |
| Published: |
Chuiko Institute of Surface Chemistry National Academy of Sciences of Ukraine
2014
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| Online Access: | https://surfacezbir.com.ua/index.php/surface/article/view/551 |
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| Journal Title: | Surface |
| Download file: |  |
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Surface| Summary: | Тhе water colloids nanocomposite particles of magnetite /hydroxyapatite/doxorubicin/polyethylene glycol/sodium oleate are produced. Particle represented as a structure of core-shell and contained magnetite nanoparticles on the surface modifier, the drug - an anthracycline antibiotic doxorubicin and combined stabilizer. It is shown that the magnetization curves are in the form of colloids characteristic superparamagnets and calculations within the framework of the Langevin theory of paramagnetism in satisfactory agreement with the experimental data . By magnetic measurements with higher reliability determined by the geometrical parameters of the synthesized nanocomposite particles that correlate with the experimental results independent researchers . The resulting actual material will be useful in the practical use of magnetic colloids and nanocomposites in cancer therapy . |
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