Біоактивні композити на основі високодисперсного кремнезему, олігосахаридів та N-ацетил-D-глюкозаміну
Composites based on ultrafine silica, oligosaccharides (sucrose, raffinose) and aminosugar (N-acetyl-D-glucosamine) were created by the method of noncovalent adsorption from solutions. It was found out that adsorption of aminosugar molecules on the surface of ultrafine silica preliminary modified by...
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| Date: | 2014 |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | Russian |
| Published: |
Chuiko Institute of Surface Chemistry National Academy of Sciences of Ukraine
2014
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| Online Access: | https://surfacezbir.com.ua/index.php/surface/article/view/557 |
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| Journal Title: | Surface |
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Surface| Summary: | Composites based on ultrafine silica, oligosaccharides (sucrose, raffinose) and aminosugar (N-acetyl-D-glucosamine) were created by the method of noncovalent adsorption from solutions. It was found out that adsorption of aminosugar molecules on the surface of ultrafine silica preliminary modified by oligosaccharides decreased by several times. Synthesized samples were investigated by means of IR-spectroscopy. It was shown that interaction of N-acetyl-D-glucosamine with surface of ultrafine silica-oligosaccharide resulted in formation of hydrogen bonds between СО- and NН- groups of aminosugar and silanol groups of silica. It was found out by the method of lasser-doppler spectroscopy that biological activity of composite UFS-Sucr-GlcNAc was much lower than that of UFS-Raf-GlcNAc. |
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