Влияние ингибитора анионного транспорта DIDS на устойчивость эритроцитов к изменению осмотических и температурных параметров среды

Влияние ингибитора анионного транспорта DIDS на устойчивость эритроцитов к изменению осмотических и температурных параметров среды

Erythrocyte sensitivity to posthypertonic lysis (PHL) was established to be dependent on dehydration medium composition, duration of hypertonic incubation and rehydration medium temperature. DIDS anion transport inhibitor causes a manifested protective effect on erythrocytes under PHL conditions whe...

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Bibliographic Details
Date:2006
Main Authors: Melikhova, S. V., Nipot, E. E., Bondarenko, V. A.
Format: Article
Language:English
Published: Publishing House ‘Akademperiodyka’ of the National Academy of Sciences of Ukraine; Institute for Problems of Cryobiology and Cryomedicine 2006
Subjects:
еритроцити
постгіпертонічний лізіс
електролит
неелектролит
Online Access:https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/581
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Journal Title:Problems of Cryobiology and Cryomedicine

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Problems of Cryobiology and Cryomedicine
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Summary:Erythrocyte sensitivity to posthypertonic lysis (PHL) was established to be dependent on dehydration medium composition, duration of hypertonic incubation and rehydration medium temperature. DIDS anion transport inhibitor causes a manifested protective effect on erythrocytes under PHL conditions when dehydration medium comprises a non-electrolyte. DIDS protective effect is slightly manifested and depends on rehydration medium temperature under dehydration in electrolyte solution. The factor, controlling erythrocyte sensitivity to PHL is assumed to be the rate of volume changes in erythrocytes at both incubation stages.

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