Влияние барбитуратов и лидокаина на устойчивость эритроцитов к гипертоническому гемолизу

Dynamics of erythrocyte hemolysis under transferring them into hypertonic solution (4.0 mol/l NaCl) with introduced barbital, phenobarbital and lidocaine at 37 and 0°C has been studied. Barbiturates and lidocaine were established to increase cell integrity under hypertony at 37 and 0°C. Protective...

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Bibliographic Details
Date:2006
Main Authors: Prokopenko, N. V., Bondarenko, V. A.
Format: Article
Language:English
Published: Publishing House ‘Akademperiodyka’ of the National Academy of Sciences of Ukraine; Institute for Problems of Cryobiology and Cryomedicine 2006
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Online Access:https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/582
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Journal Title:Problems of Cryobiology and Cryomedicine

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Problems of Cryobiology and Cryomedicine
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Summary:Dynamics of erythrocyte hemolysis under transferring them into hypertonic solution (4.0 mol/l NaCl) with introduced barbital, phenobarbital and lidocaine at 37 and 0°C has been studied. Barbiturates and lidocaine were established to increase cell integrity under hypertony at 37 and 0°C. Protective effect is more manifested in phenobarbital. Under preliminary cell dehydration the erythrocyte integrity augments after dehydration in moderately hypertonic media. In that case barbiturates and lidocaine increase cell integrity as well.