Деякі фізичні аспекти застосування наночастинок при діагностиці і лікуванні онкологічних захворювань

• Дата: 2016
• Автор: Lerman, L. B.
• Формат: Стаття
• Мова: Російська
• Опубліковано: Chuiko Institute of Surface Chemistry National Academy of Sciences of Ukraine 2016
• Онлайн доступ: https://surfacezbir.com.ua/index.php/surface/article/view/626
• Назва журналу: Surface

In this work proposer sets a goal to analyze general possibilities in principle of using gold and bimetallic nanoparticles with a silver core and a gold shell, and magnetic composite particles in cancer medicine. New solutions of electrodynamics and thermal conductivity connected problems for layered spherical and cylindrical particles are obtained. The results of calculated and experimental research of magnetic fields and technical characteristics of the applicators for the model field sources are presented. The devised method gives an opportunity of determining the configuration of magnetic systems to localize the domain of effective magnetic field action. Performed experiments set the values of magnetic moments of nanoparticles’ aggregates. Kinematic characteristics of the motion of magnetic nanoparticles in blood vessels under the action of the external field are determined, and conditions of carriers’ retention in the target organ are established. Obtained relations to calculate the temperature fields in the vicinity of nanoparticles are allowed to link the temperature in the cell and interstitial fluid with the characteristics of the electromagnetic field, and thus sets to achieve the required values of temperature, electric field strength and magnetic induction of the external field.