Вплив органічних розчинників і доксорубіцину на кластеризацію води, що зв’язана ДНК
Water bounded by DNA molecules is in several states corresponding to strongly associated water (SAW), two types of weakly associated water (WAW) and crystallizing water bound to basic sites. Weakly polar chloroform medium stabilizes the forms of weakly associated water but addition of polar DMSO inh...
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| Date: | 2010 |
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| Main Authors: | , , , , , |
| Format: | Article |
| Language: | Russian |
| Published: |
Chuiko Institute of Surface Chemistry National Academy of Sciences of Ukraine
2010
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| Online Access: | https://www.cpts.com.ua/index.php/cpts/article/view/65 |
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| Journal Title: | Chemistry, Physics and Technology of Surface |
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Chemistry, Physics and Technology of Surface| Summary: | Water bounded by DNA molecules is in several states corresponding to strongly associated water (SAW), two types of weakly associated water (WAW) and crystallizing water bound to basic sites. Weakly polar chloroform medium stabilizes the forms of weakly associated water but addition of polar DMSO inhibits the formation of one of WAWs. Intercalation of hydrated DNA molecules by doxorubicin diminishes the amounts of WAW and enhances of SAW contribution. |
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