Влияние рН и ионного состава среды на устойчивость изолированных гепатоцитов крыс к гиперосмотическому стрессу

Влияние рН и ионного состава среды на устойчивость изолированных гепатоцитов крыс к гиперосмотическому стрессу

The influence of the media with different cation and anion composition on rat’s isolated hepatocyte resistance to the hyperosmotic stress effect under different pH medium was studied. It was demonstrated that a damaging effect increased in K+ - Na+ - Li+ cation series; CH3COO- – Cl- – NO3- ani...

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Bibliographische Detailangaben
Datum:2004
Hauptverfasser: Sereda, T. P., Lezhanin, S. N., Koptelov, V. A., Bondarenko, V. A.
Format: Artikel
Sprache:English
Veröffentlicht: Publishing House ‘Akademperiodyka’ of the National Academy of Sciences of Ukraine; Institute for Problems of Cryobiology and Cryomedicine 2004
Schlagworte:
Гепатоцит
рН
осмолярність
Online Zugang:https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/703
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Назва журналу:Problems of Cryobiology and Cryomedicine

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Problems of Cryobiology and Cryomedicine
Beschreibung
Zusammenfassung:The influence of the media with different cation and anion composition on rat’s isolated hepatocyte resistance to the hyperosmotic stress effect under different pH medium was studied. It was demonstrated that a damaging effect increased in K+ - Na+ - Li+ cation series; CH3COO- – Cl- – NO3- anion series. A pH decrease results in the augmentation of cell resistance in all observed media, a pH increase, in contrast, reduces the cell resistance to hyperosmotic stress. A temperature decrease levels the effects of both ion medium composition and alkaline pH.

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