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ASYMMETRIC SYNTHESIS OF CHI-CONSTRAINED GLUTAMIC ACIDS AND RELATED COMPOUNDS VIA MICHAEL ADDITION REACTIONS

Michael addition reactions involving nucleophilic glycine equivalents and α,β-unsaturated carboxylic acid derivatives offer a concise and generalized methodological approach to synthesizing a family of χ-constrained five-carbon-atom amino acids. These amino acids play a crucial role in de novo pepti...

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Bibliographic Details
Date:2024
Main Authors: Wzorek, Alicja, Sorochinsky, Alexander, Klika, Karel, Ono, Taizo, Han, Jianlin, Soloshonok, Vadim
Format: Article
Language:English
Published: V.I.Vernadsky Institute of General and Inorganic Chemistry 2024
Online Access:https://ucj.org.ua/index.php/journal/article/view/685
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Journal Title:Ukrainian Chemistry Journal

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Ukrainian Chemistry Journal

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