NEW DRUGS ON THE PHARMACEUTICAL MARKET CONTAINING FLUORINE AND RESIDUES OF TAILOR-MADE AMINO ACIDS(Review)
This article profiles five newly drugs containing fluorine along with fragments of amino acids or their derivatives approved by the FDA in 2024. These pharmaceuticals include Voydeya® (danicopan), Ojemda® (tovorafenib), Itovebi® (inavolisib), Scemblix® (asciminib), and Revuforj® (revumenib). For ea...
Saved in:
| Date: | 2024 |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
V.I.Vernadsky Institute of General and Inorganic Chemistry
2024
|
| Online Access: | https://ucj.org.ua/index.php/journal/article/view/689 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Journal Title: | Ukrainian Chemistry Journal |
Institution
Ukrainian Chemistry Journal| _version_ | 1860506946430304256 |
|---|---|
| author | Han, Jianlin Wzorek, Alicja Dhawan, Gagan Zhang, Wei Sorochinsky, Alexander Baecker, Daniel Ono, Taizo Klika, Karel Soloshonok, Vadim |
| author_facet | Han, Jianlin Wzorek, Alicja Dhawan, Gagan Zhang, Wei Sorochinsky, Alexander Baecker, Daniel Ono, Taizo Klika, Karel Soloshonok, Vadim |
| author_sort | Han, Jianlin |
| baseUrl_str | https://ucj.org.ua/index.php/journal/oai |
| collection | OJS |
| datestamp_date | 2026-03-23T11:24:58Z |
| description | This article profiles five newly drugs containing fluorine along with fragments of amino acids or their derivatives approved by the FDA in 2024. These pharmaceuticals include Voydeya® (danicopan), Ojemda® (tovorafenib), Itovebi® (inavolisib), Scemblix® (asciminib), and Revuforj® (revumenib). For each drug, we discuss the discovery, therapeutic areas of application, and detailed chemical synthesis. |
| doi_str_mv | 10.33609/2708-129X.90.9.2024.31-56 |
| first_indexed | 2025-09-24T17:43:58Z |
| format | Article |
| id | oai:ojs2.1444248.nisspano.web.hosting-test.net:article-689 |
| institution | Ukrainian Chemistry Journal |
| keywords_txt_mv | keywords |
| language | English |
| last_indexed | 2026-03-23T18:47:19Z |
| publishDate | 2024 |
| publisher | V.I.Vernadsky Institute of General and Inorganic Chemistry |
| record_format | ojs |
| spelling | oai:ojs2.1444248.nisspano.web.hosting-test.net:article-6892026-03-23T11:24:58Z NEW DRUGS ON THE PHARMACEUTICAL MARKET CONTAINING FLUORINE AND RESIDUES OF TAILOR-MADE AMINO ACIDS(Review) Han, Jianlin Wzorek, Alicja Dhawan, Gagan Zhang, Wei Sorochinsky, Alexander Baecker, Daniel Ono, Taizo Klika, Karel Soloshonok, Vadim Fluorine, Tailor-made amino acids, Pharmaceutical drugs, Drug design, Synthesis, Bioactivity. This article profiles five newly drugs containing fluorine along with fragments of amino acids or their derivatives approved by the FDA in 2024. These pharmaceuticals include Voydeya® (danicopan), Ojemda® (tovorafenib), Itovebi® (inavolisib), Scemblix® (asciminib), and Revuforj® (revumenib). For each drug, we discuss the discovery, therapeutic areas of application, and detailed chemical synthesis. V.I.Vernadsky Institute of General and Inorganic Chemistry 2024-10-25 Article Article Organic chemistry Органическая xимия Органічна xімія application/pdf https://ucj.org.ua/index.php/journal/article/view/689 10.33609/2708-129X.90.9.2024.31-56 Ukrainian Chemistry Journal; Vol. 90 No. 9 (2024): Ukrainian Chemistry Journal; 31-56 Украинский химический журнал; Том 90 № 9 (2024): Ukrainian Chemistry Journal; 31-56 Український хімічний журнал; Том 90 № 9 (2024): Ukrainian Chemistry Journal; 31-56 2708-129X 2708-1281 en https://ucj.org.ua/index.php/journal/article/view/689/343 |
| spellingShingle | Han, Jianlin Wzorek, Alicja Dhawan, Gagan Zhang, Wei Sorochinsky, Alexander Baecker, Daniel Ono, Taizo Klika, Karel Soloshonok, Vadim NEW DRUGS ON THE PHARMACEUTICAL MARKET CONTAINING FLUORINE AND RESIDUES OF TAILOR-MADE AMINO ACIDS(Review) |
| title | NEW DRUGS ON THE PHARMACEUTICAL MARKET CONTAINING FLUORINE AND RESIDUES OF TAILOR-MADE AMINO ACIDS(Review) |
| title_full | NEW DRUGS ON THE PHARMACEUTICAL MARKET CONTAINING FLUORINE AND RESIDUES OF TAILOR-MADE AMINO ACIDS(Review) |
| title_fullStr | NEW DRUGS ON THE PHARMACEUTICAL MARKET CONTAINING FLUORINE AND RESIDUES OF TAILOR-MADE AMINO ACIDS(Review) |
| title_full_unstemmed | NEW DRUGS ON THE PHARMACEUTICAL MARKET CONTAINING FLUORINE AND RESIDUES OF TAILOR-MADE AMINO ACIDS(Review) |
| title_short | NEW DRUGS ON THE PHARMACEUTICAL MARKET CONTAINING FLUORINE AND RESIDUES OF TAILOR-MADE AMINO ACIDS(Review) |
| title_sort | new drugs on the pharmaceutical market containing fluorine and residues of tailor-made amino acids(review) |
| topic_facet | Fluorine Tailor-made amino acids Pharmaceutical drugs Drug design Synthesis Bioactivity. |
| url | https://ucj.org.ua/index.php/journal/article/view/689 |
| work_keys_str_mv | AT hanjianlin newdrugsonthepharmaceuticalmarketcontainingfluorineandresiduesoftailormadeaminoacidsreview AT wzorekalicja newdrugsonthepharmaceuticalmarketcontainingfluorineandresiduesoftailormadeaminoacidsreview AT dhawangagan newdrugsonthepharmaceuticalmarketcontainingfluorineandresiduesoftailormadeaminoacidsreview AT zhangwei newdrugsonthepharmaceuticalmarketcontainingfluorineandresiduesoftailormadeaminoacidsreview AT sorochinskyalexander newdrugsonthepharmaceuticalmarketcontainingfluorineandresiduesoftailormadeaminoacidsreview AT baeckerdaniel newdrugsonthepharmaceuticalmarketcontainingfluorineandresiduesoftailormadeaminoacidsreview AT onotaizo newdrugsonthepharmaceuticalmarketcontainingfluorineandresiduesoftailormadeaminoacidsreview AT klikakarel newdrugsonthepharmaceuticalmarketcontainingfluorineandresiduesoftailormadeaminoacidsreview AT soloshonokvadim newdrugsonthepharmaceuticalmarketcontainingfluorineandresiduesoftailormadeaminoacidsreview |