NEW DRUGS ON THE PHARMACEUTICAL MARKET CONTAINING FLUORINE AND RESIDUES OF TAILOR-MADE AMINO ACIDS

This article profiles five newly drugs containing fluorine along with fragments of amino acids or their derivatives approved by the FDA in 2024. These pharmaceuticals include Voy­deya® (danicopan), Ojemda® (tovorafenib), Itovebi® (inavolisib), Scemblix® (asciminib), and Revuforj® (revumenib). For ea...

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Date:2024
Main Authors: Han, Jianlin, Wzorek, Alicja, Dhawan, Gagan, Zhang, Wei, Sorochinsky, Alexander, Baecker, Daniel, Ono, Taizo, Klika, Karel, Soloshonok, Vadim
Format: Article
Language:English
Published: V.I.Vernadsky Institute of General and Inorganic Chemistry 2024
Online Access:https://ucj.org.ua/index.php/journal/article/view/689
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Journal Title:Ukrainian Chemistry Journal

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Ukrainian Chemistry Journal
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spelling oai:ojs2.1444248.nisspano.web.hosting-test.net:article-6892025-03-21T18:56:27Z NEW DRUGS ON THE PHARMACEUTICAL MARKET CONTAINING FLUORINE AND RESIDUES OF TAILOR-MADE AMINO ACIDS Han, Jianlin Wzorek, Alicja Dhawan, Gagan Zhang, Wei Sorochinsky, Alexander Baecker, Daniel Ono, Taizo Klika, Karel Soloshonok, Vadim Fluorine, Tailor-made amino acids, Pharmaceutical drugs, Drug design, Synthesis, Bioactivity. This article profiles five newly drugs containing fluorine along with fragments of amino acids or their derivatives approved by the FDA in 2024. These pharmaceuticals include Voy­deya® (danicopan), Ojemda® (tovorafenib), Itovebi® (inavolisib), Scemblix® (asciminib), and Revuforj® (revumenib). For each drug, we discuss the discovery, therapeutic areas of application, and detailed chemical synthesis. V.I.Vernadsky Institute of General and Inorganic Chemistry 2024-10-25 Article Article Organic chemistry Органическая xимия Органічна xімія application/pdf https://ucj.org.ua/index.php/journal/article/view/689 10.33609/2708-129X.90.9.2024.31-56 Ukrainian Chemistry Journal; Vol. 90 No. 9 (2024): Ukrainian Chemistry Journal; 31-56 Украинский химический журнал; Том 90 № 9 (2024): Ukrainian Chemistry Journal; 31-56 Український хімічний журнал; Том 90 № 9 (2024): Ukrainian Chemistry Journal; 31-56 2708-129X 2708-1281 en https://ucj.org.ua/index.php/journal/article/view/689/343
institution Ukrainian Chemistry Journal
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datestamp_date 2025-03-21T18:56:27Z
collection OJS
language English
topic_facet Fluorine
Tailor-made amino acids
Pharmaceutical drugs
Drug design
Synthesis
Bioactivity.
format Article
author Han, Jianlin
Wzorek, Alicja
Dhawan, Gagan
Zhang, Wei
Sorochinsky, Alexander
Baecker, Daniel
Ono, Taizo
Klika, Karel
Soloshonok, Vadim
spellingShingle Han, Jianlin
Wzorek, Alicja
Dhawan, Gagan
Zhang, Wei
Sorochinsky, Alexander
Baecker, Daniel
Ono, Taizo
Klika, Karel
Soloshonok, Vadim
NEW DRUGS ON THE PHARMACEUTICAL MARKET CONTAINING FLUORINE AND RESIDUES OF TAILOR-MADE AMINO ACIDS
author_facet Han, Jianlin
Wzorek, Alicja
Dhawan, Gagan
Zhang, Wei
Sorochinsky, Alexander
Baecker, Daniel
Ono, Taizo
Klika, Karel
Soloshonok, Vadim
author_sort Han, Jianlin
title NEW DRUGS ON THE PHARMACEUTICAL MARKET CONTAINING FLUORINE AND RESIDUES OF TAILOR-MADE AMINO ACIDS
title_short NEW DRUGS ON THE PHARMACEUTICAL MARKET CONTAINING FLUORINE AND RESIDUES OF TAILOR-MADE AMINO ACIDS
title_full NEW DRUGS ON THE PHARMACEUTICAL MARKET CONTAINING FLUORINE AND RESIDUES OF TAILOR-MADE AMINO ACIDS
title_fullStr NEW DRUGS ON THE PHARMACEUTICAL MARKET CONTAINING FLUORINE AND RESIDUES OF TAILOR-MADE AMINO ACIDS
title_full_unstemmed NEW DRUGS ON THE PHARMACEUTICAL MARKET CONTAINING FLUORINE AND RESIDUES OF TAILOR-MADE AMINO ACIDS
title_sort new drugs on the pharmaceutical market containing fluorine and residues of tailor-made amino acids
description This article profiles five newly drugs containing fluorine along with fragments of amino acids or their derivatives approved by the FDA in 2024. These pharmaceuticals include Voy­deya® (danicopan), Ojemda® (tovorafenib), Itovebi® (inavolisib), Scemblix® (asciminib), and Revuforj® (revumenib). For each drug, we discuss the discovery, therapeutic areas of application, and detailed chemical synthesis.
publisher V.I.Vernadsky Institute of General and Inorganic Chemistry
publishDate 2024
url https://ucj.org.ua/index.php/journal/article/view/689
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first_indexed 2025-09-24T17:43:58Z
last_indexed 2025-09-24T17:43:58Z
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