EFFECTIVE METHOD FOR PRODUCING 2-STYRYLPYRIMIDIN-4(3H)-ONES

• Дата: 2025
• Автори: Yavolovskii, Arkadii, Grishchuk, Lidiya, Pluzhnik-Glagyr, Sergei, Kamalov, Gerbert
• Формат: Стаття
• Мова: English
• Опубліковано: V.I.Vernadsky Institute of General and Inorganic Chemistry 2025
• Онлайн доступ: https://ucj.org.ua/index.php/journal/article/view/713
• Назва журналу: Ukrainian Chemistry Journal

A convenient scheme for the synthesis of a series of compounds of (E)-6-R-2-styryl­pyrimidin-(4H)-ones by reduction of 2-(2-oxo-2-arylethylidene)-2,3-dihydropyrimidin-4(1H)-ones with sodium borohydride was developed followed by dehydration of the obtained 2-(2-hydroxy-2-arylethyl)pyrimidin-­4(3H)-­o...