CUTTING-EDGE STRATEGIES IN THE ASYMMETRIC SYNTHESIS OF α-AMINOCYCLOPROPANE CARBOXYLIC ACIDS: ESSENTIAL SCAFFOLDS FOR DRUG DISCOVERY

• Дата: 2025
• Автори: Wzorek, Alicja, Han, Jianlin, Ono, Taizo, Klika, Karel, Baecker, Daniel, Zhang, Wei, Soloshonok, Vadim
• Формат: Стаття
• Мова: Англійська
• Опубліковано: V.I.Vernadsky Institute of General and Inorganic Chemistry 2025
• Онлайн доступ: https://ucj.org.ua/index.php/journal/article/view/754
• Назва журналу: Ukrainian Chemistry Journal

α-Aminocyclopropanecarboxylic acid (ACC) and its derivatives are widely distributed in the plant kingdom, fulfilling diverse roles ranging from regulation of plant life cycles to defensive mechanisms. The sterically constrained structure of ACC has proven invaluable in the design of numerous drugs,...