Хімія дифлуорометиленфосфонатів: історія, сучасний стан і перспективи

• Date: 2022
• Main Authors: Shevchuk, Mykhailo V., Röschenthaler, Gerd-Volker
• Format: Article
• Language: English
• Published: V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine 2022
• Subjects: дифлуорометиленфосфонати; фосфінати; фосфіноксиди; фосфорилдифлуорометилювання; фосфорилювання
• Online Access: https://bioorganica.com.ua/index.php/journal/article/view/12
• Journal Title: Ukrainica Bioorganica Acta

Difluoromethylene phosphonates are non-hydrolyzable bioisosteres of phosphates. They have proven their efficiency as inhibitors of the enzymes that specialize in utilizing these essential biogenic molecules. Difluoromethylene phosphonates show a broad spectrum of biological activity and are used as...