Синтез нових 1-гідроксі-1,1-бісфосфонових кислот
A synthetic method for the preparation of 1-hydroxyalkyl-1,1-bisphosphonic and 1-hydroxycycloalkyl-1,1-bisphosphonic acids, commonly known as dronic acids, has been developed. These compounds were obtained through the formation of the corresponding silyl derivatives at key stages of the synthesis. T...
Збережено в:
| Дата: | 2025 |
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| Автори: | , , |
| Формат: | Стаття |
| Мова: | Англійська |
| Опубліковано: |
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine
2025
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| Теми: | |
| Онлайн доступ: | https://bioorganica.com.ua/index.php/journal/article/view/123 |
| Теги: |
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| Назва журналу: | Ukrainica Bioorganica Acta |
Репозитарії
Ukrainica Bioorganica Acta| Резюме: | A synthetic method for the preparation of 1-hydroxyalkyl-1,1-bisphosphonic and 1-hydroxycycloalkyl-1,1-bisphosphonic acids, commonly known as dronic acids, has been developed. These compounds were obtained through the formation of the corresponding silyl derivatives at key stages of the synthesis. The developed method provides a simple and convenient approach for the preparation of hydroxybisphosphonates. The resulting compounds are promising substances with potential biological activity |
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