Перетворення заміщених 3-гідрокси-4-[(2Е)-3-арилпроп-2-еноїл]-1,5-дигідро-2Н-пірол-2-онів під дією I2/ДМСО у похідні 2-арил-5,6-дигідропірано[2,3-с]пірол-4,7-діонів
The effective and simple synthetic preparative procedure for obtaining of various derivatives of 2-aryl-5,6-dihydropyrano[2,3-c]pyrrole-4,7-diones applying the I2/DMSO oxidation of 3-hydroxy-4-[(2E)-3-arylprop-2-enoyl]-1,5-dihydro-2H-pyrrol-2-ones was developed. This protocol was found to be compati...
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| Date: | 2021 |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Published: |
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine
2021
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| Subjects: | |
| Online Access: | https://bioorganica.com.ua/index.php/journal/article/view/20 |
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| Journal Title: | Ukrainica Bioorganica Acta |
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Ukrainica Bioorganica Acta| Summary: | The effective and simple synthetic preparative procedure for obtaining of various derivatives of 2-aryl-5,6-dihydropyrano[2,3-c]pyrrole-4,7-diones applying the I2/DMSO oxidation of 3-hydroxy-4-[(2E)-3-arylprop-2-enoyl]-1,5-dihydro-2H-pyrrol-2-ones was developed. This protocol was found to be compatible with a wide range of substituents and gave the reliable synthetic pathway for the obtaining of target compounds with a wide range of substituents under mild conditions. All obtained substances can be easily isolated and purified by crystallization without application of more complex and labour intensive purification methods |
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