Переключаємі за рахунок умов багатокомпонентні реакції 5-аміно-3-(метилтіо)-1,2,4-триазолу, ароматичних альдегідів та піровиноградної кислоти

• Date: 2020
• Author Affiliations: Yana I. Sakhno — State Scientific Institution “Institute for Single Crystals” of the NAS of Ukraine, 60 Nauky Ave., Kharkiv, 61072, Ukraine; Maksym V. Mykhailenko — State Scientific Institution “Institute for Single Crystals” of the NAS of Ukraine, 60 Nauky Ave., Kharkiv, 61072, Ukraine; V.N. Karazin Kharkiv National University, 4 Svobody Sq., Kharkiv, 61077, Ukraine; Maksim A. Kolosov — V.N. Karazin Kharkiv National University, 4 Svobody Sq., Kharkiv, 61077, Ukraine; Elena H. Shvets — V.N. Karazin Kharkiv National University, 4 Svobody Sq., Kharkiv, 61077, Ukraine; Vladimir I. Musatov — State Scientific Institution “Institute for Single Crystals” of the NAS of Ukraine, 60 Nauky Ave., Kharkiv, 61072, Ukraine; Natalia V. Chorna — State Scientific Institution “Institute for Single Crystals” of the NAS of Ukraine, 60 Nauky Ave., Kharkiv, 61072, Ukraine; Sergey M. Desenko — State Scientific Institution “Institute for Single Crystals” of the NAS of Ukraine, 60 Nauky Ave., Kharkiv, 61072, Ukraine; Valentyn A. Chebanov — State Scientific Institution “Institute for Single Crystals” of the NAS of Ukraine, 60 Nauky Ave., Kharkiv, 61072, Ukraine; V.N. Karazin Kharkiv National University, 4 Svobody Sq., Kharkiv, 61077, Ukraine
• Keywords: keywords
• Main Authors: Sakhno, Yana I., Mykhailenko, Maksym V., Kolosov, Maksim A., Shvets, Elena H., Musatov, Vladimir I., Chorna, Natalia V., Desenko, Sergey M., Chebanov, Valentyn A.
• Format: Article
• Language: English
• Published: V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine 2020
• Subjects: 5-аміно-3-(метилтіо)-1,2,4-триазол; багатокомпонентна реакція; ультразвук; піровиноградна кислота; гетероциклізація
• Online Access: https://bioorganica.com.ua/index.php/journal/article/view/37
• Journal Title: Ukrainica Bioorganica Acta

The multicomponent reactions of 5-amino-3-methylthio-1,2,4-triazole with aromatic aldehydes and pyruvic acid were studied using conventional thermal heating and ultrasonic activation at room temperature. Under conventional heating, dihydrotriazolopyrimidine derivatives were formed in both two- and t...