Каскадні реакції альдольного приєднання та циклізації на основі хірального комплексу Ni(II) основи Шифа гліцину

• Date: 2021
• Author Affiliations: Yupiao Zou — College of Chemical Engineering, Nanjing Forestry University, 159 Lonpan Road, Nanjing, 210037, China; Zizhen Yin — College of Chemical Engineering, Nanjing Forestry University, 159 Lonpan Road, Nanjing, 210037, China; Haibo Mei — College of Chemical Engineering, Nanjing Forestry University, 159 Lonpan Road, Nanjing, 210037, China; Hiroyuki Konno — Department of Biochemical Engineering, Graduate School of Science and Technology, Yamagata University, Yonezawa, Yamagata 992-8510, Japan; Hiroki Moriwaki — Hamari Chemicals Ltd., 1-19-40, Nankokita, Suminoe-ku, Osaka, 559-0034, Japan; Vadim A. Soloshonok — Department of Organic Chemistry I, Faculty of Chemistry, University of the Basque Country UPV/EHU, Paseo Manuel Lardizábal 3, 20018 San Sebastián, Spain; IKERBASQUE, Basque Foundation for Science, Maria Diaz de Haro 3, 48013 Bilbao, Spain; Jianlin Han — College of Chemical Engineering, Nanjing Forestry University, 159 Lonpan Road, Nanjing, 210037, China
• Keywords: keywords
• Main Authors: Zou, Yupiao, Yin, Zizhen, Mei, Haibo, Konno, Hiroyuki, Moriwaki, Hiroki, Soloshonok, Vadim A., Han, Jianlin
• Format: Article
• Language: English
• Published: V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine 2021
• Subjects: асиметричний синтез; альдольне приєднання; специфічні неприродні амінокислоти; Ni(II) комплекси; основи Шифа; каскадні/доміно/тандемні реакції
• Online Access: https://bioorganica.com.ua/index.php/journal/article/view/42
• Journal Title: Ukrainica Bioorganica Acta

Using platform of a new type of chiral Ni(II) complex of glycine Schiff base we designed addition-cyclization reaction cascade to explore aspects of kinetic/thermodynamic formation of the corresponding (S)(2S,3S)/(S)(2S,3R) diastereomers. It was found that the final lactone products reflect the the...