Синтез нового 1-бензоїлгексагідро-2Н-піроло[3,4-d]піримідин-2,4(3Н)-діону

We report an efficient [3+2] cycloaddition involving non-stabilized electron-rich azomethine ylides and 1,3-dibenzoyl-pyrimidine-2,4(1H,3H)-dione. The 1,3-dipole was prepared in situ under TFA catalysis, and we obtained the product in good yield and with full control of the regioselectivity

Gespeichert in:
Bibliographische Detailangaben
Datum:2025
Hauptverfasser: Melnychuk, Pavlo V., Shablykin, Oleg V.
Format: Artikel
Sprache:English
Veröffentlicht: V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine 2025
Schlagworte:
Online Zugang:https://bioorganica.com.ua/index.php/journal/article/view/99
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Назва журналу:Ukrainica Bioorganica Acta

Institution

Ukrainica Bioorganica Acta
Beschreibung
Zusammenfassung:We report an efficient [3+2] cycloaddition involving non-stabilized electron-rich azomethine ylides and 1,3-dibenzoyl-pyrimidine-2,4(1H,3H)-dione. The 1,3-dipole was prepared in situ under TFA catalysis, and we obtained the product in good yield and with full control of the regioselectivity