Modern views on the role of main components of stroma and tumor microinvironment in invasion, migration and metastasis

• Date: 2023
• Main Authors: Naleskina, L.A., Kunska, L.M., Chekhun, V.F.
• Format: Article
• Language: English
• Published: PH Akademperiodyka 2023
• Subjects: activated fibroblasts; collagen; extracellular matrix; invasion; matrix metalloproteinases; metastasis; migration; myofibroblasts; tumor microenvironment; tumor progression; tumor-associated fibroblasts
• Online Access: https://exp-oncology.com.ua/index.php/Exp/article/view/2020-4-3
• Journal Title: Experimental Oncology

Summary. The review presents modern ideas about tumor microenvironment, which most researchers recognize as the main “player” in tumor cell invasion, cell migration and metastasis. The current data on the main components of the stroma and the microenvironment, which play the role of the driving forc...