Granulosa and theca cell tumor in rat’s ovary after modified Biskind operation
Summary. Background: Earlier, we described morphological changes in rat ovaries in different terms after Biskind’s operation elucidating the factors that affect the precancerous conditions and ovarian neoplasms appearance. The aim of the research was to identify tumor nature on the 120th day after m...
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| Datum: | 2023 |
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PH Akademperiodyka
2023
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| Назва журналу: | Experimental Oncology |
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Experimental Oncology| _version_ | 1856543484643639296 |
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| author | Shamrai, D. Koshik, E. Melnyk, N. |
| author_facet | Shamrai, D. Koshik, E. Melnyk, N. |
| author_sort | Shamrai, D. |
| baseUrl_str | |
| collection | OJS |
| datestamp_date | 2023-10-11T16:43:48Z |
| description | Summary. Background: Earlier, we described morphological changes in rat ovaries in different terms after Biskind’s operation elucidating the factors that affect the precancerous conditions and ovarian neoplasms appearance. The aim of the research was to identify tumor nature on the 120th day after modified Biskind’s operation using immunohistochemical approach. Results: We described morphological changes in rat ovaries on the 120th day after Biskind’s operation, demonstrated development of theca-granulosa cell tumors, and differentiated between Sertoli-Leydig cell tumors and theca-granulosa cell tumors using monoclonal antibodies against Ingibin-alfa, Calretinin, Melan А. Conclusion: Modified Biskind’s model could be used to study sex-cord tumors in rat ovaries. |
| first_indexed | 2025-07-17T12:15:54Z |
| format | Article |
| id | oai:ojs2.ex.aqua-time.com.ua:article-154 |
| institution | Experimental Oncology |
| language | English |
| last_indexed | 2025-07-17T12:15:54Z |
| publishDate | 2023 |
| publisher | PH Akademperiodyka |
| record_format | ojs |
| spelling | oai:ojs2.ex.aqua-time.com.ua:article-1542023-10-11T16:43:48Z Granulosa and theca cell tumor in rat’s ovary after modified Biskind operation Granulosa and theca cell tumor in rat’s ovary after modified Biskind operation Shamrai, D. Koshik, E. Melnyk, N. Biskind model, granulosa cell tumor, ovary, sex cord tumor, theca cell tumor Biskind model, granulosa cell tumor, ovary, sex cord tumor, theca cell tumor Summary. Background: Earlier, we described morphological changes in rat ovaries in different terms after Biskind’s operation elucidating the factors that affect the precancerous conditions and ovarian neoplasms appearance. The aim of the research was to identify tumor nature on the 120th day after modified Biskind’s operation using immunohistochemical approach. Results: We described morphological changes in rat ovaries on the 120th day after Biskind’s operation, demonstrated development of theca-granulosa cell tumors, and differentiated between Sertoli-Leydig cell tumors and theca-granulosa cell tumors using monoclonal antibodies against Ingibin-alfa, Calretinin, Melan А. Conclusion: Modified Biskind’s model could be used to study sex-cord tumors in rat ovaries. Summary. Background: Earlier, we described morphological changes in rat ovaries in different terms after Biskind’s operation elucidating the factors that affect the precancerous conditions and ovarian neoplasms appearance. The aim of the research was to identify tumor nature on the 120th day after modified Biskind’s operation using immunohistochemical approach. Results: We described morphological changes in rat ovaries on the 120th day after Biskind’s operation, demonstrated development of theca-granulosa cell tumors, and differentiated between Sertoli-Leydig cell tumors and theca-granulosa cell tumors using monoclonal antibodies against Ingibin-alfa, Calretinin, Melan А. Conclusion: Modified Biskind’s model could be used to study sex-cord tumors in rat ovaries. PH Akademperiodyka 2023-05-30 Article Article application/pdf https://exp-oncology.com.ua/index.php/Exp/article/view/2020-4-9 10.32471/exp-oncology.2312-8852.vol-42-no-4.15424 Experimental Oncology; Vol. 42 No. 4 (2020): Experimental Oncology; 306-309 Експериментальна онкологія; Том 42 № 4 (2020): Експериментальна онкологія; 306-309 2312-8852 1812-9269 10.32471/exp-oncology.2312-8852.vol-42-no-4 en https://exp-oncology.com.ua/index.php/Exp/article/view/2020-4-9/2020-4-9 Copyright (c) 2023 Experimental Oncology https://creativecommons.org/licenses/by-nc/4.0/ |
| spellingShingle | Biskind model granulosa cell tumor ovary sex cord tumor theca cell tumor Shamrai, D. Koshik, E. Melnyk, N. Granulosa and theca cell tumor in rat’s ovary after modified Biskind operation |
| title | Granulosa and theca cell tumor in rat’s ovary after modified Biskind operation |
| title_alt | Granulosa and theca cell tumor in rat’s ovary after modified Biskind operation |
| title_full | Granulosa and theca cell tumor in rat’s ovary after modified Biskind operation |
| title_fullStr | Granulosa and theca cell tumor in rat’s ovary after modified Biskind operation |
| title_full_unstemmed | Granulosa and theca cell tumor in rat’s ovary after modified Biskind operation |
| title_short | Granulosa and theca cell tumor in rat’s ovary after modified Biskind operation |
| title_sort | granulosa and theca cell tumor in rat’s ovary after modified biskind operation |
| topic | Biskind model granulosa cell tumor ovary sex cord tumor theca cell tumor |
| topic_facet | Biskind model granulosa cell tumor ovary sex cord tumor theca cell tumor Biskind model granulosa cell tumor ovary sex cord tumor theca cell tumor |
| url | https://exp-oncology.com.ua/index.php/Exp/article/view/2020-4-9 |
| work_keys_str_mv | AT shamraid granulosaandthecacelltumorinratsovaryaftermodifiedbiskindoperation AT koshike granulosaandthecacelltumorinratsovaryaftermodifiedbiskindoperation AT melnykn granulosaandthecacelltumorinratsovaryaftermodifiedbiskindoperation |