Prognostic significance of microRNA-200b and ERCC1 expression in tumor cells of patients with esophageal cancer

• Date: 2023
• Main Authors: Kirkilevsky, S.I., Krakhmalev, P.S., Malyshok, N.V., Zadvornyi, T.V., Borikun, T.V., Yalovenko, T.M.
• Format: Article
• Language: English
• Published: PH Akademperiodyka 2023
• Subjects: aggressiveness of cancer; ERCC1; esophageal cancer; miRNA 200b
• Online Access: https://exp-oncology.com.ua/index.php/Exp/article/view/2020-3-3
• Journal Title: Experimental Oncology

Summary. Background: The development of malignant tumors, including esophageal cancer (EC), could be associated with impaired expression of oncosuppressive miRNA-200b and еxcision repair cross-complementing group-1 (ERCC1), a protein involved in DNA repair and alternative splicing. Aim: To investiga...