Detection of breast cancer presenting as a mass in women with dense breasts — digital breast tomosynthesis versus full-field digital mammography

• Datum: 2023
• Hauptverfasser: Babkina, T.M., Dykan, I.M., Gurando, A.V., Suleimenova, D.M., Kozarenko, T.M., Bozhok, Ye.M., Stuley, V.A.
• Format: Artikel
• Sprache: English
• Veröffentlicht: PH Akademperiodyka 2023
• Schlagworte: breast cancer; dense breast; digital breast tomosynthesis; full-field digital mammography
• Online Zugang: https://exp-oncology.com.ua/index.php/Exp/article/view/2020-3-5
• Назва журналу: Experimental Oncology

Summary. Aim: To evaluate the sensitivity and specificity of digital breast tomosynthesis compared with full-field digital mammography in detection of breast cancer presenting as a mass in women with dense breasts. Маterials and Methods: This study included 347 asymptomatic and symptomatic patients with dense breasts who underwent full-field digital mammography, digital breast tomosynthesis and hand-held full breast ultrasound. 57 core-needle biopsies were performed. Pathology included 31 invasive cancers and 26 non-cancerous lesions. Results: Sensitivity of full-field digital mammography was 61.3% [0.422–0.789] and sensitivity of digital breast tomosynthesis was 77.4% [0.589–0.904]. Specificity of full-field digital mammography was 92.7% [0.893–0.953] that was 2.2% lower than the specificity of digital breast tomosynthesis — 94.9% [0.919–0.971]. Conclusion: Results of our study showed superior sensitivity and specificity of digital breast tomosynthesis compared to full-field digital mammography for detection of malignant masses in women with dense breasts.