Effect of valproic acid and zebularine on SOCS-1 and SOCS-3 gene expression in colon carcinoma SW48 cell line

• Date: 2023
• Main Authors: Sanaei, M., Kavoosi, F., Behjoo, H.
• Format: Article
• Language: English
• Published: PH Akademperiodyka 2023
• Subjects: colon carcinoma; SOCS-1; SOCS-3; valproic acid; zebularine
• Online Access: https://exp-oncology.com.ua/index.php/Exp/article/view/2020-3-13
• Journal Title: Experimental Oncology

Summary. Background: Two epigenetic modifications such as histone acetylation and DNA methylation have been known as critical players of gene regulation. Hypermethylation and deacetylation of suppressors of cytokine signaling family SOCS-1 and SOCS-3 have been shown in many solid c...