Analysis of immunoglobulin heavy variable chain rearrangement in chronic lymphocytic leukemia patients among Chornobyl clean-up workers

• Date: 2023
• Main Authors: Abramenko, I.V., Bilous, N.I., Chumak, A.A., Dyagil, I.S., Martina, Z.V.
• Format: Article
• Language: English
• Published: PH Akademperiodyka 2023
• Subjects: chronic lymphocytic leukemia; immunoglobulin variable heavy chain (IGHV) rearrangement; ionizing radiation
• Online Access: https://exp-oncology.com.ua/index.php/Exp/article/view/2020-3-16
• Journal Title: Experimental Oncology

Summary. Background: A number of epidemiological studies have shown an elevated radiation-associated risk for chronic lymphocytic leukemia (CLL). The aim of the paper was to analyze immunoglobulin heavy variable chain (IGHV) rearrangement and IGHV usage in CLL cases associated with ionizing...