Peculiarities of abnormal karyotypes formation in therapy-related acute leukemias

• Date: 2023
• Main Authors: Andreieva, S.V., Kyselova, O.A., Serbin, I.M., Alkhimova, O.G.
• Format: Article
• Language: English
• Published: PH Akademperiodyka 2023
• Subjects: chromosomal abnormalities; chromothripsis; complex karyotype; prognostic significance; therapy-related leukemia
• Online Access: https://exp-oncology.com.ua/index.php/Exp/article/view/2020-2-7
• Journal Title: Experimental Oncology

Summary. Aim: To determine ways of formation of abnormal karyotypes in two clinical cases of secondary acute leukemias of myeloid and lymphoid lineages. Material and Methods: Bone marrow cells of one patient with therapy-related acute monoblastic/monocytic leukemia and one patient with therapy-relat...