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Conjugation of new DNA vaccine with polyethylenimine induces cellular immune response and tumor regression in neuroblastoma mouse model

Summary. Aim: To estimate immunogenicity and antitumor effect of new DNA vaccine against neuroblastoma using tyrosine hydroxylase as an antigen and linear polyethylenimine (PEI) 20 kDa as a synthetic DNA carrier in syngeneic mouse tumor model. Materials and Methods: DNA vaccine was made by...

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Bibliographic Details
Date:	2023
Main Authors:	Stegantseva, M.V., Shinkevich, V.A., Tumar, E.M., Meleshko, A.N.
Format:	Article
Language:	English
Published:	PH Akademperiodyka 2023
Subjects:	DNA vaccine neuroblastoma polyethylenimine tyrosine hydroxylase
Online Access:	https://exp-oncology.com.ua/index.php/Exp/article/view/2020-2-11
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Journal Title:	Experimental Oncology

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Experimental Oncology

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