HRM screening of the UBC9 gene encoding the SUMO-E2-conjugating enzyme — case-control study in breast cancer

• Date: 2023
• Main Authors: Bialik, P., Wysokinski, D., Slomka, M., Morawiec, Z., Strapagiel, D., Wozniak, K.
• Format: Article
• Language: English
• Published: PH Akademperiodyka 2023
• Subjects: breast cancer; gene polymorphism; high resolution melting method; sumoylation; UBC9 gene
• Online Access: https://exp-oncology.com.ua/index.php/Exp/article/view/2020-2-12
• Journal Title: Experimental Oncology

Summary. Aim: UBC9 (E2) small ubiquitin-like modifier conjugating enzyme plays a key role in the post-translational modification of proteins named sumoylation. Defects in small ubiquitin-like modifier modification may contribute to breast carcinogenesis. In the present work, we examined UBC9&nbs...