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Rapamycin-induced autophagy plays a pro-survival role by enhancing up-regulation of intracellular ferritin expression in acute lymphoblastic leukemia

Summary. Elevated mammalian target of rapamycin (mTOR) signaling has been reported to correlate with poor prognosis in acute lymphoblastic leukemia (ALL) patients. Rapamycin, an mTOR kinase inhibitor, and also a potent autophagy inducer, could not only effectively reverse glucocorticoid resistance,...

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Datum:	2023
Hauptverfasser:	Gong, Y., Wu, J., Yang, R., Zhang, L., Ma, Z.
Format:	Artikel
Sprache:	Englisch
Veröffentlicht:	PH Akademperiodyka 2023
Schlagworte:	acute lymphoblastic leukemia autophagy ciclopirox olamine ferritin rapamycin
Online Zugang:	https://exp-oncology.com.ua/index.php/Exp/article/view/2020-1-3
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!
Назва журналу:	Experimental Oncology

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Experimental Oncology

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