Antiproliferative and apoptotic effects of anti-human HB-EGF neutralizing polyclonal antibodies in vitro

• Date: 2023
• Main Authors: Siromolot, A.A., Krynina, O.I., Kolybo, D.V., Komisarenko, S.V.
• Format: Article
• Language: English
• Published: PH Akademperiodyka 2023
• Subjects: antibodies.; cancer treatment.; HB-EGF; mitogenic activation; receptors
• Online Access: https://exp-oncology.com.ua/index.php/Exp/article/view/2020-1-8
• Journal Title: Experimental Oncology

Summary. Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a member of the epidermal growth factor family and has a variety of physiological and pathophysiological functions. Also, HB-EGF plays a pivotal role in progression of different tumors. So, HB-EGF seems to be a target mo...