Metformin enhances cytotoxic action of dichloroacetate against Lewis lung carcinoma cells in vitro

• Дата: 2023
• Автори: Kolesnik, D.L., Pyaskovskaya, O.N., Gorbach, O., Solyanik, G.I.
• Формат: Стаття
• Мова: English
• Опубліковано: PH Akademperiodyka 2023
• Теми: Lewis lung carcinoma; metformin; sodium dichloroacetate
• Онлайн доступ: https://exp-oncology.com.ua/index.php/Exp/article/view/2020-1-11
• Назва журналу: Experimental Oncology

Summary. Tumor cell metabolism is considered one of the hallmarks of cancer. This concept is exploited in the development of new ways of anticancer therapy based on the use of substances capable of changing drastically bioenergetic metabolism of tumor cells. Among them, sodium dichloroace­tate (DCA)...