Deletions in metastatic colorectal cancer with chromothripsis

• Date: 2023
• Main Authors: Skuja, E., Butane, D., Nakazawa-Miklasevica, M., Daneberga, Z., Purkalne, G., Miklasevics, E.
• Format: Article
• Language: English
• Published: PH Akademperiodyka 2023
• Subjects: chromothripsis; deletion; metastatic colorectal cancer; progression free survival
• Online Access: https://exp-oncology.com.ua/index.php/Exp/article/view/2019-4-3
• Journal Title: Experimental Oncology

Summary. Aim: In our previously reported study, we found a correlation between DNA massive fragmentation and increased progression free survival (PFS) in metastatic colorectal cancer (mCRC), but not overall survival. The aim of this study is to find overlapping deleted genome regio...