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Apoptosis-inducing effect of spiroaminopyrimidine analogue in NB4 leukemia cells via down-regulation of BIRC5 expression

Summary. Aim: It has been reported that spiroaminopyrimidine derivatives inhibited the growth and proliferation of various cancer cell lines. In the present study, we evaluated cytotoxic and apoptosis-inducing effects of 2,4-diamino-1,3-diazaspiro[5.5]-9-tert-butyl-2, 4-diene-5-carbonitril (9-tBAP)...

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Datum:	2023
Hauptverfasser:	Dehghan Nayeri, M.J., Mahdavi, M., Fazeli, H., Hosseinpour Feizi, M.A.
Format:	Artikel
Sprache:	Englisch
Veröffentlicht:	PH Akademperiodyka 2023
Schlagworte:	apoptosis cell cycle NB4 cell line spiroaminopyrimidine
Online Zugang:	https://exp-oncology.com.ua/index.php/Exp/article/view/2019-4-5
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!
Назва журналу:	Experimental Oncology

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Experimental Oncology

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