Non-linear dynamics theory and malignant melanoma

Summary. Chaos theory (nonlinear dynamics) defines cancer as a complex adaptive system in which each cyclic point corresponds to the bifurcation at which changes in signaling pathways emerge. Quantitative assessment of chaos in digital medical images such as electron microscopy, histology and cytolo...

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Дата:2023
Автори: Orel, V.E., Korovin, S.I., Molnár, J., Orel, V.B.
Формат: Стаття
Мова:English
Опубліковано: PH Akademperiodyka 2023
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Онлайн доступ:https://exp-oncology.com.ua/index.php/Exp/article/view/2019-4-8
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Назва журналу:Experimental Oncology

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Experimental Oncology
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spelling oai:ojs2.ex.aqua-time.com.ua:article-2182023-10-11T16:42:06Z Non-linear dynamics theory and malignant melanoma Non-linear dynamics theory and malignant melanoma Orel, V.E. Korovin, S.I. Molnár, J. Orel, V.B. cancer, chaos (nonlinear dynamics), hierarchical levels, melanoma cancer, chaos (nonlinear dynamics), hierarchical levels, melanoma Summary. Chaos theory (nonlinear dynamics) defines cancer as a complex adaptive system in which each cyclic point corresponds to the bifurcation at which changes in signaling pathways emerge. Quantitative assessment of chaos in digital medical images such as electron microscopy, histology and cytology sections collected from patients with malignant cutaneous melanoma employed the following calculation parameters: the irregularity of external contours, internal heterogeneity based on brightness distribution of macromo­lecules, chromosomes, organelles, inclusion bodies, cells and tissues, kurtosis, entropy and the asymmetry coefficient. The present study undertook a nonlinear analysis of the chaotic hierarchy of malignant melanoma. However, considerably more studies will need to be carried out to determine the exact interrelationship between different levels of the hierarchy in the biological system. Multidisciplinary collaborations are therefore essential to find evidence to answer questions that remain open to researchers and oncologists. Summary. Chaos theory (nonlinear dynamics) defines cancer as a complex adaptive system in which each cyclic point corresponds to the bifurcation at which changes in signaling pathways emerge. Quantitative assessment of chaos in digital medical images such as electron microscopy, histology and cytology sections collected from patients with malignant cutaneous melanoma employed the following calculation parameters: the irregularity of external contours, internal heterogeneity based on brightness distribution of macromo­lecules, chromosomes, organelles, inclusion bodies, cells and tissues, kurtosis, entropy and the asymmetry coefficient. The present study undertook a nonlinear analysis of the chaotic hierarchy of malignant melanoma. However, considerably more studies will need to be carried out to determine the exact interrelationship between different levels of the hierarchy in the biological system. Multidisciplinary collaborations are therefore essential to find evidence to answer questions that remain open to researchers and oncologists. PH Akademperiodyka 2023-06-02 Article Article application/pdf https://exp-oncology.com.ua/index.php/Exp/article/view/2019-4-8 10.32471/exp-oncology.2312-8852.vol-41-no-4.13672 Experimental Oncology; Vol. 41 No. 4 (2019): Experimental Oncology; 291-299 Експериментальна онкологія; Том 41 № 4 (2019): Експериментальна онкологія; 291-299 2312-8852 1812-9269 10.32471/exp-oncology.2312-8852.vol-41-no-4 en https://exp-oncology.com.ua/index.php/Exp/article/view/2019-4-8/2019-4-8 Copyright (c) 2023 Experimental Oncology https://creativecommons.org/licenses/by-nc/4.0/
institution Experimental Oncology
baseUrl_str
datestamp_date 2023-10-11T16:42:06Z
collection OJS
language English
topic cancer
chaos (nonlinear dynamics)
hierarchical levels
melanoma
spellingShingle cancer
chaos (nonlinear dynamics)
hierarchical levels
melanoma
Orel, V.E.
Korovin, S.I.
Molnár, J.
Orel, V.B.
Non-linear dynamics theory and malignant melanoma
topic_facet cancer
chaos (nonlinear dynamics)
hierarchical levels
melanoma
cancer
chaos (nonlinear dynamics)
hierarchical levels
melanoma
format Article
author Orel, V.E.
Korovin, S.I.
Molnár, J.
Orel, V.B.
author_facet Orel, V.E.
Korovin, S.I.
Molnár, J.
Orel, V.B.
author_sort Orel, V.E.
title Non-linear dynamics theory and malignant melanoma
title_short Non-linear dynamics theory and malignant melanoma
title_full Non-linear dynamics theory and malignant melanoma
title_fullStr Non-linear dynamics theory and malignant melanoma
title_full_unstemmed Non-linear dynamics theory and malignant melanoma
title_sort non-linear dynamics theory and malignant melanoma
title_alt Non-linear dynamics theory and malignant melanoma
description Summary. Chaos theory (nonlinear dynamics) defines cancer as a complex adaptive system in which each cyclic point corresponds to the bifurcation at which changes in signaling pathways emerge. Quantitative assessment of chaos in digital medical images such as electron microscopy, histology and cytology sections collected from patients with malignant cutaneous melanoma employed the following calculation parameters: the irregularity of external contours, internal heterogeneity based on brightness distribution of macromo­lecules, chromosomes, organelles, inclusion bodies, cells and tissues, kurtosis, entropy and the asymmetry coefficient. The present study undertook a nonlinear analysis of the chaotic hierarchy of malignant melanoma. However, considerably more studies will need to be carried out to determine the exact interrelationship between different levels of the hierarchy in the biological system. Multidisciplinary collaborations are therefore essential to find evidence to answer questions that remain open to researchers and oncologists.
publisher PH Akademperiodyka
publishDate 2023
url https://exp-oncology.com.ua/index.php/Exp/article/view/2019-4-8
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AT korovinsi nonlineardynamicstheoryandmalignantmelanoma
AT molnarj nonlineardynamicstheoryandmalignantmelanoma
AT orelvb nonlineardynamicstheoryandmalignantmelanoma
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