Macrophages — a perspective target for antineoplastic immunotherapy

• Date: 2023
• Main Authors: Karaman, О.М., Ivanchenko, A.V., Chekhun, V.F.
• Format: Article
• Language: English
• Published: PH Akademperiodyka 2023
• Subjects: M1/M2 macrophages; malignant tumors; plasticity; polarization
• Online Access: https://exp-oncology.com.ua/index.php/Exp/article/view/2019-4-9
• Journal Title: Experimental Oncology

Summary. The review discusses the data on the functional/phenotypic M1/M2 types of macrophages and their chimeric forms, the molecular mechanisms of polarization of these cells, and their role in the development of malignant tumors. Information on the prognostic value of the presence (densi...