Cytostatic cancer therapy modulates monocyte-macrophage cell functions: how it impacts on treatment outcomes

• Date: 2023
• Main Authors: Patysheva, M., Stakheyeva, M., Larionova, I., Fedorov, A., Kzhyshkowska, J., Cherdyntseva, N.
• Format: Article
• Language: English
• Published: PH Akademperiodyka 2023
• Subjects: cytostatic therapy; immunomodulation; monocytes; tumor progression; tumor-associated macrophages
• Online Access: https://exp-oncology.com.ua/index.php/Exp/article/view/2019-3-1
• Journal Title: Experimental Oncology

Summary. Macrophages are important effectors of innate immunity and the key component of the tumor microenvironment strongly influencing cancer disease outcome and efficiency of cancer therapy. Moreover, recent data have shown that monocytes as macrophage precursors can impact on tumor ability to pr...