Моlecular mechanisms of initiation of carcinogenesis in the testis

• Date: 2023
• Main Authors: Bazalytska, S.V., Persidsky, Y., Romanenko, A.M.
• Format: Article
• Language: English
• Published: PH Akademperiodyka 2023
• Subjects: blood-testis barrier; germ cell neoplasia in situ; germ cell tumors; ionizing radiation; male infertility; TGFβ; ubiquitin-proteasomal proteolysis
• Online Access: https://exp-oncology.com.ua/index.php/Exp/article/view/2019-3-5
• Journal Title: Experimental Oncology

Summary. In this review, literature data on the study of precancerous changes in testicular tissue and molecular changes, as well as the influence of environmental factors that can initiate carcinogenesis, were analyzed and summarized for the future determination of early diagnosis of germ cell tumo...