Prognostic factors in metastatic gastric carcinoma
Summary. Although its incidence has declined over last half-century, gastric cancer remains the second most frequent cause of cancer death in the world. The ⅔ of the patients are metastatic at diagnosis. The current study aimed to identify some determinants of survival in patients with meta...
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| Datum: | 2023 |
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PH Akademperiodyka
2023
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Experimental Oncology| _version_ | 1856543536813441024 |
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| author | Ben Kridis, W. Marrekchi, G. Mzali, R. Daoud, J. Khanfir, A. |
| author_facet | Ben Kridis, W. Marrekchi, G. Mzali, R. Daoud, J. Khanfir, A. |
| author_sort | Ben Kridis, W. |
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| datestamp_date | 2023-10-11T16:41:24Z |
| description | Summary. Although its incidence has declined over last half-century, gastric cancer remains the second most frequent cause of cancer death in the world. The ⅔ of the patients are metastatic at diagnosis. The current study aimed to identify some determinants of survival in patients with metastatic gastric carcinoma. Materials and Methods: It was a retrospective study that involved 49 patients treated with palliative chemotherapy between January 2000 and December 2010. Factors included: age, gender, performance status, metastatic diagnosis onset (at diagnosis or later); specific metastatic sites, number of metastatic localizations, response to chemotherapy, and hemoglobin rate. Results: In univariate analysis, factors associated to a better survival were: metastasis at diagnosis, good performance status, response to chemotherapy and single metastatic site. Independent factors in multivariate analysis were: metastasis at diagnosis and single metastatic site. Conclusion: Our study confirmed many determinants on survival described in the literature. |
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| format | Article |
| id | oai:ojs2.ex.aqua-time.com.ua:article-254 |
| institution | Experimental Oncology |
| language | English |
| last_indexed | 2025-07-17T12:17:06Z |
| publishDate | 2023 |
| publisher | PH Akademperiodyka |
| record_format | ojs |
| spelling | oai:ojs2.ex.aqua-time.com.ua:article-2542023-10-11T16:41:24Z Prognostic factors in metastatic gastric carcinoma Prognostic factors in metastatic gastric carcinoma Ben Kridis, W. Marrekchi, G. Mzali, R. Daoud, J. Khanfir, A. chemotherapy, gastric cancer, metastasis, prognostic factors, survival chemotherapy, gastric cancer, metastasis, prognostic factors, survival Summary. Although its incidence has declined over last half-century, gastric cancer remains the second most frequent cause of cancer death in the world. The ⅔ of the patients are metastatic at diagnosis. The current study aimed to identify some determinants of survival in patients with metastatic gastric carcinoma. Materials and Methods: It was a retrospective study that involved 49 patients treated with palliative chemotherapy between January 2000 and December 2010. Factors included: age, gender, performance status, metastatic diagnosis onset (at diagnosis or later); specific metastatic sites, number of metastatic localizations, response to chemotherapy, and hemoglobin rate. Results: In univariate analysis, factors associated to a better survival were: metastasis at diagnosis, good performance status, response to chemotherapy and single metastatic site. Independent factors in multivariate analysis were: metastasis at diagnosis and single metastatic site. Conclusion: Our study confirmed many determinants on survival described in the literature. Summary. Although its incidence has declined over last half-century, gastric cancer remains the second most frequent cause of cancer death in the world. The ⅔ of the patients are metastatic at diagnosis. The current study aimed to identify some determinants of survival in patients with metastatic gastric carcinoma. Materials and Methods: It was a retrospective study that involved 49 patients treated with palliative chemotherapy between January 2000 and December 2010. Factors included: age, gender, performance status, metastatic diagnosis onset (at diagnosis or later); specific metastatic sites, number of metastatic localizations, response to chemotherapy, and hemoglobin rate. Results: In univariate analysis, factors associated to a better survival were: metastasis at diagnosis, good performance status, response to chemotherapy and single metastatic site. Independent factors in multivariate analysis were: metastasis at diagnosis and single metastatic site. Conclusion: Our study confirmed many determinants on survival described in the literature. PH Akademperiodyka 2023-06-05 Article Article application/pdf https://exp-oncology.com.ua/index.php/Exp/article/view/2019-2-13 10.32471/exp-oncology.2312-8852.vol-41-no-2.13283 Experimental Oncology; Vol. 41 No. 2 (2019): Experimental Oncology; 173-175 Експериментальна онкологія; Том 41 № 2 (2019): Експериментальна онкологія; 173-175 2312-8852 1812-9269 10.32471/exp-oncology.2312-8852.vol-41-no-2 en https://exp-oncology.com.ua/index.php/Exp/article/view/2019-2-13/2019-2-13 Copyright (c) 2023 Experimental Oncology https://creativecommons.org/licenses/by-nc/4.0/ |
| spellingShingle | chemotherapy gastric cancer metastasis prognostic factors survival Ben Kridis, W. Marrekchi, G. Mzali, R. Daoud, J. Khanfir, A. Prognostic factors in metastatic gastric carcinoma |
| title | Prognostic factors in metastatic gastric carcinoma |
| title_alt | Prognostic factors in metastatic gastric carcinoma |
| title_full | Prognostic factors in metastatic gastric carcinoma |
| title_fullStr | Prognostic factors in metastatic gastric carcinoma |
| title_full_unstemmed | Prognostic factors in metastatic gastric carcinoma |
| title_short | Prognostic factors in metastatic gastric carcinoma |
| title_sort | prognostic factors in metastatic gastric carcinoma |
| topic | chemotherapy gastric cancer metastasis prognostic factors survival |
| topic_facet | chemotherapy gastric cancer metastasis prognostic factors survival chemotherapy gastric cancer metastasis prognostic factors survival |
| url | https://exp-oncology.com.ua/index.php/Exp/article/view/2019-2-13 |
| work_keys_str_mv | AT benkridisw prognosticfactorsinmetastaticgastriccarcinoma AT marrekchig prognosticfactorsinmetastaticgastriccarcinoma AT mzalir prognosticfactorsinmetastaticgastriccarcinoma AT daoudj prognosticfactorsinmetastaticgastriccarcinoma AT khanfira prognosticfactorsinmetastaticgastriccarcinoma |