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Suboptimal molecular response to tyrosine kinase inhibition associated with acquisition of a T240A ABL1 kinase domain mutation in a patient with chronic myeloid leukemia

Over the last twenty years, chronic myeloid leukemia (CML) has come to be considered a paradigm for rationally selected, targeted inhibition of the disease-specific, BCR-ABL1 tyrosine kinase activity. However, a minor but significant numbers of patients either fail, or have suboptimal respo...

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Datum:	2023
Hauptverfasser:	Langabeer, S.E., Haslam, K., Crampe, M., MacDonagh, B., McHugh, J.
Format:	Artikel
Sprache:	Englisch
Veröffentlicht:	PH Akademperiodyka 2023
Schlagworte:	T240A ABL1
Online Zugang:	https://exp-oncology.com.ua/index.php/Exp/article/view/2019-1-1
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!
Назва журналу:	Experimental Oncology

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Experimental Oncology

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