DNA oxidation in patients with metastastic colorectal cancer: clinical significance of 8-hydroxy-deoxyguanosine as an independent prognostic factor

• Date: 2023
• Main Authors: Burlaka, A.A., Vovk, A.V., Burlaka, A.P., Kolesnik, O.O.
• Format: Article
• Language: English
• Published: PH Akademperiodyka 2023
• Subjects: 8-hydroxy-deoxyguanosine; colorectal cancer.; liver resection; metastases; superoxide radicals
• Online Access: https://exp-oncology.com.ua/index.php/Exp/article/view/2019-1-10
• Journal Title: Experimental Oncology

Summary. Prognosis of metastatic colorectal cancer (mCRC) patients nowadays is an important subject in the field of oncology. R0-resection of colon with primary tumor and liver metastasis remains the only treatment which significantly improves survival rate. However, recent experimental data show th...