Cover Image

DNA oxidation in patients with metastastic colorectal cancer: clinical significance of 8-hydroxy-deoxyguanosine as an independent prognostic factor

Summary. Prognosis of metastatic colorectal cancer (mCRC) patients nowadays is an important subject in the field of oncology. R0-resection of colon with primary tumor and liver metastasis remains the only treatment which significantly improves survival rate. However, recent experimental data show th...

Full description

Saved in:

Bibliographic Details
Date:	2023
Main Authors:	Burlaka, A.A., Vovk, A.V., Burlaka, A.P., Kolesnik, O.O.
Format:	Article
Language:	English
Published:	PH Akademperiodyka 2023
Subjects:	8-hydroxy-deoxyguanosine colorectal cancer. liver resection metastases superoxide radicals
Online Access:	https://exp-oncology.com.ua/index.php/Exp/article/view/2019-1-10
Tags:	Add Tag No Tags, Be the first to tag this record!
Journal Title:	Experimental Oncology

Institution

Experimental Oncology

Similar Items

Molecular mechanisms of oxidation damage and liver cell dysfunction in patients with metastatic colorectal cancer
by: Burlaka, A.P., et al.
Published: (2023)

Cytochrome P450 content in primary tumors and liver metastases of patients with metastatic colorectal cancer
by: Burlaka, A.P., et al.
Published: (2023)

Drag reducing polymers attenuate adverse effects of ischemia-reperfusion upon resection of liver metastases modeled by MC38 mouse colon adenocarcinomama
by: Burlaka, А.А., et al.
Published: (2023)

Tumor-associated redox state in metastatic colorectal cancer
by: Burlaka, A.P., et al.
Published: (2023)

Deletions in metastatic colorectal cancer with chromothripsis
by: Skuja, E., et al.
Published: (2023)

Immunocytochemical characteristics of thyrocytes in radioiodine refractory metastases of papillary thyroid cancer
by: Zelinskaya, A.
Published: (2023)

Prognostic significance of microRNA-200b and ERCC1 expression in tumor cells of patients with esophageal cancer
by: Kirkilevsky, S.I., et al.
Published: (2023)

SIGNIFICANT CONTRIBUTION OF THE DEPARTMENT OF GEOLOGY OF MINERALRS OF THE INSTITUTE OF GEOLOGICALE SCIENCES OF NAS OF UKRAINE INTO THE DEVELOPMENT OF NATIONAL GEOLOGY DURING THE UKRAINIAN INDEPENDENCE
by: Remezova, O.O., et al.
Published: (2019)

Giant DNA Viruses Infecting Unicellular Protists
by: Kyrychenko, A.M., et al.
Published: (2023)

СATALYTIC METHOD FOR THE SYNTHESIS OF 3-HYDROXY-2-NAPHTOIC ACID ANILIDE
by: Shteinberg, Leon
Published: (2022)

Prognostic factors in metastatic gastric carcinoma
by: Ben Kridis, W., et al.
Published: (2023)

Improvement of turbogenerators as a technical basis for ensuring the energy independence of Ukraine
by: Shevchenko, V. V., et al.
Published: (2021)

ABOUT COGNITIVE SIGNIFICANCE OF NEOCREATIONISM
by: Dykan, K.V.
Published: (2016)

SYNTHESIS OF 3-HYDROXY-2-NAPHTHOIC ACID ANILIDE CATALYZED BY PHOSPHORUS (III) COMPOUNDS IN VARIOUS MEDIA
by: Shteinberg, Leon
Published: (2023)

THE COMPLEX FORMATION OF PALLADIUM(II) WITH 1-HYDROXY-2-(3-PYRIDYL) ETHYLIDENEDIPHOSPHONIC (RISEDRONIC) ACID
by: Kozachkova, Oleksandra, et al.
Published: (2025)

Integer quadratic forms and extensions of subsets of linearly independent roots
by: Stekolshchik, Rafael
Published: (2025)

NANOG as prognostic factor of prostate cancer course
by: Zadvornyi, T.V., et al.
Published: (2023)

Phylogeography of the Western Populations of Stylodipus telum (Rodentia, Dipodidae) based on Mitochondrial DNA
by: Rusin, M.
Published: (2022)

Phylogeography of the Western Populations of Stylodipus telum (Rodentia, Dipodidae) based on Mitochondrial DNA
by: Rusin, M.
Published: (2022)

SIGNIFICANT CONTRIBUTION TO THE STUDY OF COAL, COAL-GAS AND PETROLEUM GEOLOGY
by: KULCHYCKA, А.A., et al.
Published: (2013)

Rapid and Efficient Method for DNA Extraction from Fungi of the Genus Morchella Dill. ex Pers.
by: Pluzhnyk, A.V., et al.
Published: (2025)

Conjugation of new DNA vaccine with polyethylenimine induces cellular immune response and tumor regression in neuroblastoma mouse model
by: Stegantseva, M.V., et al.
Published: (2023)

ENERGY EFFICIENCY OF WIND-HYDRO PUMPING STATION SIGNIFICANT POWER
by: Vasko, P., et al.
Published: (2020)

TO THE THIRTIES ANNIVERSARY OF THE INDEPENDENCE OF UKRAINEPRIORITIES IN CANCER RESEARCH: RETROSPECTIVE AND PROSPECTIVE ASPECTS
Published: (2023)

Distribution, Properties, and Practical Significance of α-Galactosidase
by: Borzova, N.V., et al.
Published: (2024)

Prognostic role of androgen receptor expression in patients with metastatic triple negative breast cancer
by: Lyalkin, S.A., et al.
Published: (2023)

Assessment of prognostic and diagnostic value of some biomarkers in hepatocellular carcinoma
by: Çavuş, B., et al.
Published: (2023)

SMALL MAMMALS OF PLEISTOCENE AND THEIR SIGNIFICANCE FOR STRATIGRAPHIC OF EASTERN EUROPE LOESS-SOIL FORMATION
by: Krokhmal, A. I.
Published: (2010)

РЕДОКС-ЗАЛЕЖНІ ОСОБЛИВОСТІ ЖИРОВОЇ ТКАНИНИ, ПУХЛИНИ, НЕЙТРОФІЛІВ ТА ТРОМБОЦИТІВ У ХВОРИХ НА МЕТАСТАТИЧНИЙ КОЛОРЕКТАЛЬНИЙ РАК
by: Burlaka, A.P., et al.
Published: (2023)

NF-kB as a potential prognostic marker and a candidate for targeted therapy of cancer
by: Gaptulbarova, K.A., et al.
Published: (2023)

On prognostication ability of active geosystems: metastability and steady transitions instead of attractors
by: Shuman, V.N.
Published: (2016)

Tumor microenvironment-derived miRNAs as prognostic markers of breast cancer
by: Lukianova, N.Yu., et al.
Published: (2023)

Carapaces of the Dnieper-Donets Basin as a New Exploration Target for significant hydrocarbon deposits
by: Petrovska, T.O., et al.
Published: (2022)

Spatial and temporal changes in Falconiformes and Strigiformes nutrition: causes, significance, consequences
by: Komarnytskyi, I., et al.
Published: (2020)

Trace Elements Zinc and Selenium: Their Significance in the Conditions of the COVID-19 Pandemic
by: Gulich, M.P., et al.
Published: (2023)

Spatial and temporal changes in Falconiformes and Strigiformes nutrition: causes, significance, consequences
by: Komarnytskyi, I., et al.
Published: (2020)

Clinical significance of serum caveolin-1 levels in gastric cancer patients
by: Tas, F., et al.
Published: (2018)

REDUCING THE ENVIRONMENTAL IMPACT AND ENERGY INDEPENDENCE OF A MEDICAL FACILITY WHEN IMPLEMENTING SOLAR PHOTOVOLTAIC PANELS
by: Olinechenko , Yu., et al.
Published: (2025)

THE ROLE OF BATTERY ENERGY STORAGE SYSTEMS (BESS) IN ENHANCING THE RESILIENCE AND ENERGY INDEPENDENCE OF UKRAINE’S POWER SYSTEM
by: Diachenko , O.
Published: (2025)

КОРОНАВІРУС SARS-COV-2 МОДИФІКУЄ ПРОТИПУХЛИННИЙ ОКИСНО-ВІДНОВЛЮВАЛЬНИЙ СТАТУС В КРОВІ ТА МІЖКЛІТИННОМУ МАТРИКСІ У ХВОРИХ НА МЕТАСТАТИЧНИЙ КОЛОРЕКТАЛЬНИЙ РАК (ПІЛОТНЕ ДОСЛІДЖЕННЯ)
by: Burlaka, A.P., et al.
Published: (2023)