Assessment of trace elements in serum of acute lymphoblastic and myeloid leukemia patients
Summary. Aim: Trace elements play a key role in human metabolism. The aim of the present study was to measure essential trace elements in the serum of patients with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). Materials and Methods: 32 patients with ALL and 16 patients with A...
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| Дата: | 2023 |
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| Автори: | , , , , |
| Формат: | Стаття |
| Мова: | Англійська |
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PH Akademperiodyka
2023
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| Онлайн доступ: | https://exp-oncology.com.ua/index.php/Exp/article/view/2019-1-14 |
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| Назва журналу: | Experimental Oncology |
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Experimental Oncology| _version_ | 1856543546433077248 |
|---|---|
| author | Valadbeigi, S. Javadian, S. Ebrahimi-Rad, M. Khatami, S. Saghiri, R. |
| author_facet | Valadbeigi, S. Javadian, S. Ebrahimi-Rad, M. Khatami, S. Saghiri, R. |
| author_sort | Valadbeigi, S. |
| baseUrl_str | |
| collection | OJS |
| datestamp_date | 2025-04-30T12:08:14Z |
| description | Summary. Aim: Trace elements play a key role in human metabolism. The aim of the present study was to measure essential trace elements in the serum of patients with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). Materials and Methods: 32 patients with ALL and 16 patients with AML were studied. The control group consisted of 36 subjects. Serum levels of the trace elements selenium, copper and zinc were measured by spectrophotometry. Results: The mean of copper concentrations in the groups of patients with AML and ALL was significantly higher than in the control group (p < 0.0001), whereas serum levels of selenium and zinc were significantly lower in AML patients (p < 0.0001). Also in ALL patients the levels of selenium and zinc were significantly decreased compared with the control group (p < 0.0001; p = 0.0003). Conclusion: Our results indicate that the levels of zinc and selenium are significantly decreased and copper levels are significantly increased in the serum of patients with acute leukemia (AML, ALL). |
| first_indexed | 2025-07-17T12:17:17Z |
| format | Article |
| id | oai:ojs2.ex.aqua-time.com.ua:article-272 |
| institution | Experimental Oncology |
| language | English |
| last_indexed | 2025-07-17T12:17:17Z |
| publishDate | 2023 |
| publisher | PH Akademperiodyka |
| record_format | ojs |
| spelling | oai:ojs2.ex.aqua-time.com.ua:article-2722025-04-30T12:08:14Z Assessment of trace elements in serum of acute lymphoblastic and myeloid leukemia patients Assessment of trace elements in serum of acute lymphoblastic and myeloid leukemia patients Valadbeigi, S. Javadian, S. Ebrahimi-Rad, M. Khatami, S. Saghiri, R. acute lymphoblastic leukemia, acute myeloid leukemia., copper, selenium, spectrophotometry, zinc. acute lymphoblastic leukemia, acute myeloid leukemia., copper, selenium, spectrophotometry, zinc. Summary. Aim: Trace elements play a key role in human metabolism. The aim of the present study was to measure essential trace elements in the serum of patients with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). Materials and Methods: 32 patients with ALL and 16 patients with AML were studied. The control group consisted of 36 subjects. Serum levels of the trace elements selenium, copper and zinc were measured by spectrophotometry. Results: The mean of copper concentrations in the groups of patients with AML and ALL was significantly higher than in the control group (p < 0.0001), whereas serum levels of selenium and zinc were significantly lower in AML patients (p < 0.0001). Also in ALL patients the levels of selenium and zinc were significantly decreased compared with the control group (p < 0.0001; p = 0.0003). Conclusion: Our results indicate that the levels of zinc and selenium are significantly decreased and copper levels are significantly increased in the serum of patients with acute leukemia (AML, ALL). Summary. Aim: Trace elements play a key role in human metabolism. The aim of the present study was to measure essential trace elements in the serum of patients with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). Materials and Methods: 32 patients with ALL and 16 patients with AML were studied. The control group consisted of 36 subjects. Serum levels of the trace elements selenium, copper and zinc were measured by spectrophotometry. Results: The mean of copper concentrations in the groups of patients with AML and ALL was significantly higher than in the control group (p < 0.0001), whereas serum levels of selenium and zinc were significantly lower in AML patients (p < 0.0001). Also in ALL patients the levels of selenium and zinc were significantly decreased compared with the control group (p < 0.0001; p = 0.0003). Conclusion: Our results indicate that the levels of zinc and selenium are significantly decreased and copper levels are significantly increased in the serum of patients with acute leukemia (AML, ALL). PH Akademperiodyka 2023-06-08 Article Article application/pdf https://exp-oncology.com.ua/index.php/Exp/article/view/2019-1-14 10.32471/exp-oncology.2312-8852.vol-41-no-1.12730 Experimental Oncology; Vol. 41 No. 1 (2019): Experimental Oncology; 69-71 Експериментальна онкологія; Том 41 № 1 (2019): Експериментальна онкологія; 69-71 2312-8852 1812-9269 10.32471/exp-oncology.2312-8852.vol-41-no-1 en https://exp-oncology.com.ua/index.php/Exp/article/view/2019-1-14/2019-1-14 Copyright (c) 2023 Experimental Oncology https://creativecommons.org/licenses/by-nc/4.0/ |
| spellingShingle | acute lymphoblastic leukemia acute myeloid leukemia. copper selenium spectrophotometry zinc. Valadbeigi, S. Javadian, S. Ebrahimi-Rad, M. Khatami, S. Saghiri, R. Assessment of trace elements in serum of acute lymphoblastic and myeloid leukemia patients |
| title | Assessment of trace elements in serum of acute lymphoblastic and myeloid leukemia patients |
| title_alt | Assessment of trace elements in serum of acute lymphoblastic and myeloid leukemia patients |
| title_full | Assessment of trace elements in serum of acute lymphoblastic and myeloid leukemia patients |
| title_fullStr | Assessment of trace elements in serum of acute lymphoblastic and myeloid leukemia patients |
| title_full_unstemmed | Assessment of trace elements in serum of acute lymphoblastic and myeloid leukemia patients |
| title_short | Assessment of trace elements in serum of acute lymphoblastic and myeloid leukemia patients |
| title_sort | assessment of trace elements in serum of acute lymphoblastic and myeloid leukemia patients |
| topic | acute lymphoblastic leukemia acute myeloid leukemia. copper selenium spectrophotometry zinc. |
| topic_facet | acute lymphoblastic leukemia acute myeloid leukemia. copper selenium spectrophotometry zinc. acute lymphoblastic leukemia acute myeloid leukemia. copper selenium spectrophotometry zinc. |
| url | https://exp-oncology.com.ua/index.php/Exp/article/view/2019-1-14 |
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