The role of the genetic abnormalities, epigenetic and microRNA in the prognosis of chronic lymphocytic leukemia

• Дата: 2018
• Автори: Tari, K., Shamsi, Z., Reza Ghafari, H., Atashi, A., Shahjahani, M., Abroun, S.
• Формат: Стаття
• Мова: English
• Опубліковано: PH Akademperiodyka 2018
• Теми: chronic lymphocytic leukemia; epigenetics; genetic mutation
• Онлайн доступ: https://exp-oncology.com.ua/index.php/Exp/article/view/2018-4-3
• Назва журналу: Experimental Oncology

Summary. Chronic lymphocytic leukemia (CLL) is increased proliferation of B-cells with peripheral blood and bone marrow involvement, which is usually observed in older people. Genetic mutations, epigenetic changes and miRs play a role in CLL pathogenesis. Del 11q, del l17q...