BER gene polymorphisms associated with key molecular events in bladder cancer

• Date: 2018
• Main Authors: Smal, M.P., Kuzhir, T.D., Savina, N.V., Nikitchenko, N.V., Rolevich, A.I., Krasny, S.A., Goncharova, R.I.
• Format: Article
• Language: English
• Published: PH Akademperiodyka 2018
• Subjects: BER gene polymorphisms; bladder cancer; LOH; methylation; mutability
• Online Access: https://exp-oncology.com.ua/index.php/Exp/article/view/2018-4-5
• Journal Title: Experimental Oncology

Summary. Aim: Base excision repair (BER) gene polymorphisms are known to play an independent role in predisposition to developing different cancers as well as to be associated with clinicopathological traits of the disease modifying its clinical outcomes. One of the underlying mechanisms is presumed...