ВІРГІНАЛЬНИЙ РЕЦИДИВ ГІГАНТОМАСТІЇ (ГІПЕРТРОФІЇ ГРУДНОЇ ЗАЛОЗИ): КЛІНІЧНИЙ ВИПАДОК

• Datum: 2024
• Hauptverfasser: CHESHUK, V., ANIKUSKO, M., KOZINA, V., ULISHCHENKO, V., MALEC, M.
• Format: Artikel
• Sprache: English
• Veröffentlicht: PH Akademperiodyka 2024
• Schlagworte: ідіопатична гігантомастія; віргінальна рецидивна гігантомастія; псевдоангіоматозна стромальна гіперплазія (ПАСГ); ендогенна гормональна стимуляція; редукційна мамопластика
• Online Zugang: https://exp-oncology.com.ua/index.php/Exp/article/view/385
• Назва журналу: Experimental Oncology

Virginal gigantomastia (VGM) is a benign disease of the breasts without a clearly established etiology. The treatment of VGM remains a problem. The conservative treatment is not effective while surgery is too traumatic. Most specialists recommend subcutaneous mastectomy with immediate implant reconstruction or reduction mammoplasty. The reduction mammoplasty with adjuvant hormone therapy is a variant of treatment of young patients with a risk of recurrence. We present a case of a patient with VGM who was operated in 2014. Reduction mammoplasty was performed. After 9 years, the patient had a relapse and second surgery, resection of the breasts with reduction mammoplasty. Tissues with cysts, fibrosis, hamartomas, and fibroadenomas were dissected. Histopathology revealed extensive fibrosis with hamartomas and fibroadenomas. The immunohistochemical examination of the breast tissue showed a high level (70%) of estrogen and progesterone receptors expression. We prescribed hormone therapy with tamoxifen 10 mg per day. Dynamic monitoring of the treatment result and control of the disease remission was carried out. Breast-conserving surgery performed in such patients can help alleviate the psychological, social, and physical disorders caused by VGM.