РІДКІСНИЙ ВИПАДОК CD10+CD23+ ВОЛОСАТОКЛІТИННОЇ ЛЕЙКЕМІЇ З ЛЕЙКОЦИТОЗОМ. КЛІНІЧНИЙ ВИПАДОК ТА ОГЛЯД ЛІТЕРАТУРИ

A rare case of hairy cell leukemia with CD10+CD23+ expression and leukocytosis is described. The key point marker for hairy cell leukemia is the presence of the BRAF V600E mutation regardless of the leukocyte count and atypical aberrant CD10+ or CD23+ expression. The presented clinical case report i...

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Bibliographic Details
Date:2025
Main Authors: SKRYPNYK, I., MASLOVA, G., LYMANETS, T., GUSACHENKO, I., YEROSHENKO, G.
Format: Article
Language:English
Published: PH Akademperiodyka 2025
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Online Access:https://exp-oncology.com.ua/index.php/Exp/article/view/471
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Journal Title:Experimental Oncology

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Experimental Oncology
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Summary:A rare case of hairy cell leukemia with CD10+CD23+ expression and leukocytosis is described. The key point marker for hairy cell leukemia is the presence of the BRAF V600E mutation regardless of the leukocyte count and atypical aberrant CD10+ or CD23+ expression. The presented clinical case report is important for understanding the biology of hairy cell leukemia and emphasizes the role of molecular genetic testing in atypical morpho-phenotyping disease presentation.