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МОЛЕКУЛЯРНІ МАРКЕРИ В ПРОГНОЗУВАННІ РЕЗУЛЬТАТІВ ЛІКУВАННЯ ХВОРИХ НА ДИФУЗНУ ГЛІОМУ IV СТУПЕНЮ АНАПЛАЗІЇ

Aim. To assess the expression of MGMT (O6-methylguanine-DNA methyltransferase) gene by MGMT RNA abundance and the presence of IDH1/2 (isocitrate dehydrogenase) variants in glioblastoma (GBM) samples for predicting the efficacy of temozolomide (TMZ) treatment, recurrence risk, and patients’ survival....

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Bibliographic Details
Date:2025
Main Authors: Glavatskyi, O., Vasylieva, I., Malysheva, T., Chopik, N., Tsiubko, O., Shuba, I., Shmelova, A., Zemskova, O., Yakovenko, L., Pedachenko, E.
Format: Article
Language:English
Published: PH Akademperiodyka 2025
Subjects:
гліобластома
MGMT
IDH1/2
темозоломід
Online Access:https://exp-oncology.com.ua/index.php/Exp/article/view/502
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Journal Title:Experimental Oncology

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Experimental Oncology

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