KALERIIA PAVLIVNA GANINA: The Life Dedicated to Science and Mankind — On the Centennial Birthday
KALERIIA PAVLIVNA GANINA: The Life Dedicated to Science and Mankind — On the Centennial Birthday
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| Datum: | 2026 |
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| Format: | Artikel |
| Sprache: | Englisch |
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PH Akademperiodyka
2026
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| author | Scientific Council |
| author_facet | Scientific Council |
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| datestamp_date | 2026-06-14T20:08:49Z |
| description | KALERIIA PAVLIVNA GANINA: The Life Dedicated to Science and Mankind — On the Centennial Birthday |
| first_indexed | 2026-06-15T01:00:31Z |
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ISSN 1812-9269. Experimental Oncology 48 (1). 2026 77
© PH “Akademperiodyka” of the NAS of Ukraine, 2026. This is an open access article under the CC BY-NC-ND license
(https://creativecommons.org/licenses/by-nc-nd/4.0/)
Anniversary
The honored master of science and engineering of
Ukraine, laureate of the O. Bogomolets Prize, doc-
tor of medicine, professor, and distinguished
Ukrainian scientist — pathomorphologist and cy-
togeneticist — Kaleriia Pavlivna Ganina belongs to
the leading figures in Ukrainian science. She be-
longs to the outstanding national researchers who
have significantly advanced medical-biological sci-
ence through new knowledge, shaping the develop-
ment of genetic studies in cancer pathology in
Ukraine for many years. Prof. Ganina’s extensive
scientific and teaching work formed a core founda-
tion of cancer genetics in Ukraine.
Together with academician Rostislav Kavetsky,
she set up the major principles of the cytological
reactivity of the tumor-bearing host, laying down
the foundations for a new research trend in ex-
perimental oncology. The depth of critical
thought in harmony with dedication to science
was the prominent quality of Prof. Ganina, noted
by all colleagues who were fortunate to work
with her.
Kaleriia Pavlivna Ganina was born on May 20,
1926. Having graduated from a medical institute in
1949, she started her scientific and teaching career in
the network of higher medical education. In 1960,
Kaleriia Pavlivna joined the staff of Kyiv Research In-
stitute of Experimental and Clinical Oncology (now-
adays R.E. Kavetsky Institute of Experimental Patho
logy, Oncology and Radiobiology of the National
Academy of Sciences of Ukraine). The more than
40‑year research activity at this Institute was the most
fruitful period of Prof. Ganina’s scientific career.
Here, the priority trend in her studies was estab-
lished, namely, the study of cytogenetic alterations
in cancer cells and in non-malignant cells of pre-
cancerous pathologies, which laid the foundation
for the Ukrainian scholarly direction in human
cancer genetics.
Her research began with examining the clinical
and morphological features of testicular cancer, as
well as its morphogenesis and histogenesis. The re-
sults of this study enabled her to characterize the
morphological patterns of precancerous and can-
cerous lesions and to propose an algorithm for dif-
ferential diagnosis. These findings formed the basis
of her doctoral thesis “Morphology and histogene-
sis of testicular tumors.” The monograph published
under the same title became a guidebook for prac-
ticing oncologists. Prof. Ganina’s studies attracted
the attention of the global scientific community,
and she was invited to serve as a WHO expert on
KALERIIA PAVLIVNA GANINA: The Life
Dedicated to Science and Mankind —
On the Centennial Birthday
Science is the highest manifestation of human
intelligence and service to humanity
V. Vernadskyi
Kaleriia Pavlivna Ganina: the Life Dedicated to Science and Mankind — on the Centennial Birthday
the histological classification of this tumor type.
Her work contributed significantly to the develop-
ment of the unified international classification of
testicular tumors, which was later implemented in
clinical practice in Europe.
Further research by Prof. Ganina shaped know
ledge of the genetic basis underlying the process of
tumor development. She developed approaches for
the cytogenetic diagnosis of precancerous condi-
tions and cancer. Alongside the genetic alterations
in cancer cells, Prof. Ganina studied the corre-
sponding changes in somatic non-malignant cells
outside the tumor. For the first time in Ukraine,
the role of genetic factors in the origin of neo-
plasms was substantiated. Genetic alterations in
cells have been proven to precede the morphologic
manifestation of tumor growth. The analysis of ge-
netic features before the appearance of the malig-
nant growth could open the way for early cancer
detection and prognosis of the course of the dis-
ease. The multicenter clinic-genealogical studies
of cancer patients, as well as individuals at cancer
risk due to exposure to the adverse industrial fac-
tors in various regions of Ukraine, were prioritized
in scientific activities led by Prof. Ganina. Such
studies became a question of paramount impor-
tance following the Chornobyl catastrophe since
radionuclide contamination of the environment is
an essential risk factor for cancer development.
The analysis of cytogenetic alterations in the pe-
ripheral blood lymphocytes for tracking cancer de-
velopment proved the importance of genome in-
stability underlying neoplastic transformation.
Prof. Ganina has always encouraged the impor-
tance of combining cytogenetic and morphological
analyses, considering the tumor as a complex bio-
logical system wherein the morphological changes
reflect the genomic alterations.
The scientific legacy of Prof. Ganina comprises
more than 400 scientific works, including many
monographs and numerous methodical guidelines.
She was a thesis supervisor for a dozen scientists.
Prof. Ganina’s scientific school of cancer genetics
has brought together researchers of all ages, ensu
ring continuity in the advancement of this research
strand. Prof. Ganina’s followers continue to inves-
tigate cellular and genetic alterations in tumors, ad-
vancing the methods she has established in both
basic and applied research.
Prof. Ganina was a principled scientist who de-
manded the exactness of statements and the corre-
spondence of the conclusions to the results ob-
tained. She warned against the hasty generaliza-
tions. All her research activities were based on the
principles of scientific integrity, comprising the
critical analysis of the findings, the correctness of
their interpretation, and responsibility for each sci-
entific statement.
She paid particular attention to the professional
formation of young researchers, supporting them
in their research, encouraging independent think-
ing and responsibility for the results.
The colleagues and followers of Prof. Ganina
noted that she combined her high exactingness
with kindness in communication. She could enjoy
the success of her students, creating an atmosphere
of confidence and intellectual responsibility in her
research teams.
The remark by academician Borys Paton “There
is no greater honor than to serve science and hu-
manity” is the perfect one to describe the life path
and scientific accomplishments of Kaleriia Pavlivna.
The centennial birthday celebration of Kaleriia
Pavlivna Ganina offers a meaningful opportunity
to honor the distinguished scientist and reflect on
her contributions to Ukrainian science. Her name
remains an indispensable part of the history and
advancement of national oncology.
Scientific Council and scientists
of the R.E. Kavetsky Institute
of Experimental Pathology,
Oncology and Radiobiology
of the National Academy
of Sciences of Ukraine
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| spelling | oai:ojs2.ex.aqua-time.com.ua:article-6222026-06-14T20:08:49Z KALERIIA PAVLIVNA GANINA: The Life Dedicated to Science and Mankind — On the Centennial Birthday KALERIIA PAVLIVNA GANINA: The Life Dedicated to Science and Mankind — On the Centennial Birthday Scientific Council KALERIIA PAVLIVNA GANINA: The Life Dedicated to Science and Mankind — On the Centennial Birthday KALERIIA PAVLIVNA GANINA: The Life Dedicated to Science and Mankind — On the Centennial Birthday PH Akademperiodyka 2026-06-14 Article Article application/pdf https://exp-oncology.com.ua/index.php/Exp/article/view/622 Experimental Oncology; Vol. 48 No. 1 (2026): Experimental Oncology; 77-78 Експериментальна онкологія; Том 48 № 1 (2026): Експериментальна онкологія; 77-78 2312-8852 1812-9269 10.15407/exp-oncology.2026.01 en https://exp-oncology.com.ua/index.php/Exp/article/view/622/468 Copyright (c) 2026 Experimental Oncology https://creativecommons.org/licenses/by-nc-nd/4.0/ |
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| title | KALERIIA PAVLIVNA GANINA: The Life Dedicated to Science and Mankind — On the Centennial Birthday |
| title_alt | KALERIIA PAVLIVNA GANINA: The Life Dedicated to Science and Mankind — On the Centennial Birthday |
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| title_full_unstemmed | KALERIIA PAVLIVNA GANINA: The Life Dedicated to Science and Mankind — On the Centennial Birthday |
| title_short | KALERIIA PAVLIVNA GANINA: The Life Dedicated to Science and Mankind — On the Centennial Birthday |
| title_sort | kaleriia pavlivna ganina: the life dedicated to science and mankind — on the centennial birthday |
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